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- Achondroplasia
- Ambiguous Genitalia
- Anterior Pituitary Disorders
- Diabetes
- Diabetes Insipidus
- Diet and Diabetes
- DiGeorge Syndrome
- Disorders Affecting Calcium Metabolism
- Disorders Affecting the Adrenal Glands
- Disorders Affecting the Pituitary Gland
- Hyperparathyroidism
- Hypoparathyroidism
- Hypopituitarism
- Juvenile Osteoporosis
- Overactive Adrenal Glands / Cushing's Syndrome
- Overview of Diabetes
- Pheochromocytoma
- Teens and Diabetes
- Type 1 Diabetes
- Type 2 Diabetes
- Underactive Adrenal Glands / Addison's Disease
Endocrinology, Diabetes and Metabolism
Research
Endocrinology, Diabetes and Metabolism researchers at Morgan Stanley Children's Hospital are actively involved in studies focused on growth, pubertal development and diabetes.
The very active research program at Morgan Stanley Children's Hospital continues to expand. The following describes some of the more than 15 protocols currently underway.
- Studies - funded in part by the National Institutes of Health (NIH) - are focusing on the interrelationship of androgens, growth factors and insulin sensitivity in premature adrenarche, polycystic ovarian syndrome, and children born to mothers with pregnancies complicated by diabetes.
- The Columbia Clinical Center for the Bone Mineral Density in Childhood is one of five centers selected by NIH for a national project to investigate the course of body composition during normal growth and maturation, as well as the effects of specific pediatric diseases and their treatments.
- A pilot study is looking at the pattern of fat distribution in children with premature adrenarche, a possible link to development of the "metabolic syndrome" in children.
- Three projects are involved with novel treatments of pediatric endocrine disorders. One study is looking at the effect of growth hormone and GnRH agonist therapy on height, growth velocity, bone mineral accrual and body composition in congenital adrenal hyperplasia. Another project is studying the efficacy of a new method of androgen therapy for boys with pubertal failure. The Division is part of a multicenter project on the efficacy of a newly available growth factor for treatment of growth disorders.
- In collaboration with the Naomi Berri Diabetes Center, the Division is expanding research related to type I diabetes and to the childhood obesity epidemic and accompanying type II diabetes. One study is testing the effects of a unique school-based diet and exercise program on risk factors for type II diabetes in Hispanic adolescents, which will be expanded to include students from other ethnic groups. Another study, the TODAY Trial (Treatment Options for Type II Diabetes in Adolescents and Youth), seeks to determine appropriate therapy for new onset Type II Diabetes in adolescents. Laboratory studies are underway that are looking at islet cell transplantation. In addition, the Division and the Naomi Berrie Diabetes Center are conducting a trial with infants, which is focusing on the reduction of type I diabetes in children who are genetically at risk. The same investigators are also involved in the NIH-funded, multicenter TRIGR (Trial to Reduce Insulin Dependent Diabetes Mellitus in the Genetically at Risk) study.
- The Division of Endocrinology, Diabetes and Metabolism is collaborating with the Columbia University School of Dental and Oral Surgery on an NIH-sponsored oral health project for children and adolescents with type I diabetes.
- State-of-the-art research is being employed for investigating causes of diabetes-related complications.
- In collaboration with the Division of Pediatric Surgery, the division is investigating the impact and effectiveness of laparoscopic gastric banding on the treatment of morbid obesity in adolescence.
Contact
- Pediatric Endocrinology, Diabetes and Metabolism
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Directions
(212) 305-6559
